Search on: MACROPHAGE-ACTIVATING FACTORS 
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Descriptor English:   Macrophage-Activating Factors 
Descriptor Spanish:   Factores Activadores de Macrófagos 
Descriptor Portuguese:   Fatores Ativadores de Macrófagos 
Synonyms English:   Factors, Macrophage-Activating
Macrophage Activating Factors  
Tree Number:   D12.644.276.374.480.615
D12.776.467.374.480.615
D23.529.374.480.615
Definition English:   Factors secreted by stimulated lymphocytes that prime macrophages to become nonspecifically cytotoxic to tumors. They also modulate the expression of macrophage cell surface Ia antigens. One MAF is INTERFERON-GAMMA. Other factors antigenically distinct from IFN-gamma have also been identified. 
History Note English:   91 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   29033 
Unique Identifier:   D016215 

Occurrence in VHL:
 

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